|
|
S-adenosyl-L-methionine + 7-methylxanthine <=> H+ + Theobromine + S-adenosyl-L-homocysteine
|
2.1.1.159
theobromine synthase
2.1.1.160
caffeine synthase
|
–
–
|
MK
|
|
BRENDA:
BR48813
KEGG:
R07919
MetaCyc:
RXN-7598
SABIO-RK:
14237
|
|
|
|
S-adenosyl-L-methionine + Theobromine <=> H+ + Caffeine + S-adenosyl-L-homocysteine
|
2.1.1.160
caffeine synthase
|
–
|
MK
|
|
BRENDA:
BR48814
KEGG:
R07920
MetaCyc:
RXN-7599
SABIO-RK:
14238
|
|
|
|
Caffeine + NADPH + O2 + H+ <=> Theobromine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
BMK
|
|
BRENDA:
BR50577
KEGG:
R07956
MetaCyc:
RXN-11513
|
|
|
|
Caffeine + NADH + O2 + H+ <=> Theobromine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
K
|
|
BRENDA:
BR50577-a
KEGG:
R07955
MetaCyc:
RXN-11513_WOP
|
|
|
|
Theobromine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.179
methylxanthine N3-demethylase
|
–
|
MK
|
|
BRENDA:
BR50580
KEGG:
R07962
MetaCyc:
RXN-11516
|
|
|
|
Theobromine + NADH + O2 + H+ <=> 7-methylxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
BK
|
|
BRENDA:
BR50580-a
KEGG:
R07961
MetaCyc:
RXN-11516_WOP
|
|
|
|
Theobromine + O2 + NADH + H+ <=> 3-Methylxanthine + NAD+ + H2O + formaldehyde
|
1.13.12
1.14.13.128
7-methylxanthine demethylase
|
–
–
|
K
|
|
BRENDA:
BS412968
KEGG:
R07963
|
|
|
|
Theobromine + O2 + NADPH + H+ <=> 3-Methylxanthine + formaldehyde + NADP+
|
1.13.12
1.14.13.128
7-methylxanthine demethylase
|
–
–
|
K
|
|
BRENDA:
BS418269
KEGG:
R07964
|
|
|
|
Theobromine + O2 + H2O <=> 3,7-dimethyluric_acid + H2O2
|
1.17.3.2
xanthine oxidase
|
–
|
MK
|
|
KEGG:
R07978
MetaCyc:
RXN-11519
|
|
|
|
S-adenosyl-L-methionine + 3-Methylxanthine <=> H+ + Theobromine + S-adenosyl-L-homocysteine
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-7603
|
|
|
|
Theobromine + 2 O2 + 2 NADH + 2 H+ <=> xanthine + 2 NAD+ + 2 H2O + 2 formaldehyde
|
1.14.13.128
7-methylxanthine demethylase
|
–
|
|
|
BRENDA:
BS412967
|
|
|
|
Theobromine + O2 + NADH + H+ <=> 3-Methylxanthine + formaldehyde + NADP+
|
1.14.13.128
7-methylxanthine demethylase
|
–
|
|
|
BRENDA:
BS418269-a
|
|
|
|
S-adenosyl-L-methionine + 7-methylxanthosine <=> Theobromine + S-adenosyl-L-homocysteine
|
2.1.1.159
theobromine synthase
2.1.1.160
caffeine synthase
|
–
–
|
|
|
SABIO-RK:
15255
|
|